Adrien Agreste/Relationships

Nathalie Sancoeur/Mayura
Nathalie takes care of Adrien's needs, but her mostly serious nature towards him, not unlike his father, doesn't help him connect with her on any personal level. He openly acknowledges and appreciates her kindness and assistance but her professional tone when she addresses him bars him from confiding in her.

Adrien is unaware that Nathalie has been working alongside Hawk Moth (who he also doesn’t know is his father) and secretly hates his alter ego. Furthermore, he is unaware that she is Hawk Moth’s ally Mayura.

Alya Césaire/Rena Rouge
Adrien seems to trust Alya's judgment; an example of this is when he suspected Chloé was Ladybug since Alya believed it. Though there is not much interaction between them, Adrien and Alya are friendly to one another when an encounter arises. Such as when they got pair together for a project with Nino in "The Evillustrator" and when they were talking to each other about Marinette's birthday in "Befana".

As Cat Noir, he also describes her as a "brave chick" to Ladybug when she is kidnapped by the titular character in "The Pharaoh". After Ladybug left he asked Alya if she wanted to know his age but by looking at his ring he ran away in fear. In "Dark Owl", Adrien comes to Alya as Cat Noir with Ladybug to ask her for a favor in helping the Owl live out his dream. She gladly accepts, and he praises her for her good acting performance.

Cat Noir meets Rena Rouge, Alya's alter ego, in "Sapotis", welcoming her to his and Ladybug's team with open arms. After she responds to his teasing with her own teasing, he notes that he has a feeling he'll like working with her. Cat Noir and Rena Rouge working well as a team, Cat Noir helps her by giving her advice when she needs it, and he is impressed by how fast she learns. When she leaves to de-transform, he bids her farewell by saying it was a pleasure to work with her. In later episodes, he continues to work well with her.

Emilie Agreste
Though not much is known about Emilie, it is clear that Adrien intensely loves his mother and misses her very much. However, he believes that she has simply disappeared, unaware that she is actually being kept in a respiratory underneath the Agreste mansion.

He has many pictures of her on his phone and as his computer background. His father has said that Adrien and his mother were very much alike. During Christmas in "A Christmas Special", Adrien misses her due to it being his first Christmas without her and becomes depressed. His memory of her is the only thing that stops him from using his Cataclysm on an outdoor Christmas tree. He sneaks out of the house in "Gorizilla" to see a rare film she starred in, taking off his disguise in awe at seeing her onscreen.

Lila Rossi
Adrien is friendly with Lila, but he is flustered and wary by her upfront passion towards him. While he is upset when he learns the truth about her lies of being a superhero, he somewhat feels bad for her being harshly exposed by Ladybug.

In "Catalyst", Adrien is disappointed when Lila lies to the class about being in the kingdom of Achu and working on a pollution-reduction project, shaking his head in disapproval.

As Cat Noir, at first, he believes Volpina is a real new hero, being supportive of her and suggesting that Ladybug should treat her nicely. Once he figures out Volpina is Lila, he tries to reason with her as his regular self, albeit awkwardly having to note that they weren't necessarily going on a date earlier before her akumatization. His response as Cat Noir to Lila's rejection of Ladybug's apology is "Ouch..."

Santa Claus
Adrien meets Santa after running away from home, and the two become friends when Santa gives Adrien Camembert for Plagg and gives him advice on his situation with his father. Grateful for Santa's friendliness, Adrien gives him the Christmas hat Marinette made for him and invites him to celebrate Christmas with him and his family. When Santa is falsely accused of being akumatized by Ladybug, Adrien defends him by telling Ladybug that she's wrong (though she doesn't listen). After the events of Santa's real akumatization, Adrien is happy to see him and his other friends checking on his return.

Wayhem
Adrien first comes across Wayhem in “Gorizilla” after sneaking out of his house. Wayhem’s overly enthusiastic behavior towards him makes him uncomfortable and he tries to walk away from him, only for Wayhem to take a selfie with him and post it online. He is also not happy when Wayhem along with a bunch of other obsessed fans follow him everywhere.

However, after Wayhem helps him by pretending to be him in order to defeat Gorizilla and keep his identity safe (the latter unbeknownst to Wayhem), Adrien is grateful and even apologizes for asking him to take his place. He also gives him his email address, stating that if he stops constantly screaming every time he’s around, they can become friends.

Kagami Tsurugi
Adrien treats Kagami respectfully as an opponent during their match in "Riposte", and he feels guilty for his uncertain win against her, a win that makes her depressed. Though he isn't initially aware that Kagami is a girl or that her family is famous in fencing, he treats her kindly, and he encourages her to try again at battling him in a rematch with a definitive winner.

In "Frozer", Adrien asks her about his romances on Ladybug she advises him to change to targets and the two spend some time at the ice rink together. When Adrien tells her he won't give up on his love for Ladybug, Kagami accepts his choice but says she'll be waiting when he quits.

Master Wang Fu
At first, he came across Wang Fu in "Ladybug & Cat Noir (Origins - Part 1)" helping him up. Adrien officially meets Wang in "Syren", where he was shocked as the man knew his identity as Cat Noir. When he comes to the mansion Plagg introduces Wang as the Guardian of the Miraculous.

Marinette's parents
Adrien first meets Marinette's parents in "Gamer" when he comes over to practice with Marinette for a video game tournament finding them nice and friendly and enjoyed watching Tom's cooking lessons in "Despair Bear".

As Cat Noir, he welcomed their help in protecting Kim in "Animan" as well as eyed their family photo smiling at their happiness.

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Tikki
After Adrien gets his memory erased by Oblivio and detransforms he meets Tikki at first he is unsure what she is but is friendly towards her. And admires her compliment when she calls him and Marinette an effective couple from Master Fu he learns that Tikki is Marinette's kwami. But when Oblivio was defeated and his memory was restored he forget about their encounter.}}